Oncology
Fighting cancer alongside patients — stories of courage, loss, and hope
Oncologist burnout is among the highest in medicine, driven by the cumulative grief of patient losses, prognostic uncertainty, and the emotional labor of delivering terminal diagnoses, per the Journal of Clinical Oncology.
Oncology places physicians in sustained, intimate contact with mortality in a way that few other specialties replicate. The oncologist's relationship with a cancer patient often spans months or years, through cycles of treatment, remission, recurrence, and ultimately, in many cases, death. This extended proximity to the dying process — and occasionally to its inexplicable reversal — makes oncology one of the richest specialties for extraordinary medical experiences. Spontaneous remission of cancer, while rare, is a documented phenomenon: a 2023 review in the Annals of Oncology estimated the incidence at roughly 1 in 60,000 to 1 in 100,000 cancer cases, with certain tumor types showing higher rates.
What makes spontaneous remission so provocative is not merely its occurrence but its context. Oncologists report that these cases often coincide with significant psychological or spiritual events — a patient who finds purpose, reconnects with estranged family, or undergoes a profound shift in outlook. While the temptation to draw causal conclusions is scientifically premature, the correlation is consistent enough that researchers like Dr. Kelly Turner have built academic careers studying the commonalities among radical remission cases. Dr. Kolbaba's Physicians' Untold Stories includes oncologists who describe similar patterns, noting that the remissions they found most inexplicable were also those accompanied by the most dramatic psychological or spiritual transformations.
Beyond remission, oncology is a specialty saturated with end-of-life phenomena. Oncologists witness deathbed visions with unusual frequency, simply because so much of their practice involves accompanying patients through the final weeks and days of life. They describe patients who transition from agitation and fear to sudden, profound calm, often reporting the presence of deceased loved ones in the room. Palliative oncology research, including studies by Dr. Christopher Kerr at Hospice Buffalo, has documented these visions as consistent, non-pathological, and associated with significant reductions in end-of-life distress.
What Oncology Physicians Report
Oncologists contributing to Physicians' Untold Stories describe rare but indelible cases of histologically confirmed, late-stage cancers that underwent near-complete remission without adequate medical explanation — sometimes temporally linked to profound psychological or spiritual shifts in the patient's life. These spontaneous remissions, estimated at roughly 1 in 60,000 to 1 in 100,000 cases, leave lasting impressions on the treating oncologists precisely because they defy every prognostic model the specialty relies upon.
Extraordinary Phenomena in Oncology
Spontaneous Cancer Remission
Histologically confirmed malignancies that regress partially or completely without treatment or with treatment that should have been insufficient. Oncologists describe these cases as qualitatively different from expected treatment responses, often occurring in patients whose tumors were considered refractory to available therapies.
Pre-Death Serenity Shift
Terminal cancer patients who transition abruptly from distress, pain, or confusion to a state of calm lucidity in the final hours or days of life. Oncologists and oncology nurses report that this shift frequently coincides with the patient's description of seeing or communicating with deceased individuals.
Tumor Response to Psychological Events
Measurable changes in tumor markers or imaging findings that temporally correlate with significant emotional or psychological events in the patient's life, such as reconciliation, forgiveness, or spiritual experience. While psychoneuroimmunology offers partial frameworks, oncologists note cases where the magnitude and timing of the response exceed what current models predict.
Accurate Prognostic Self-Knowledge
Cancer patients who accurately predict the timing of their own death, sometimes contradicting the clinical team's prognostic estimate. Oncologists observe that these predictions are often delivered with calm certainty and prove remarkably accurate, a phenomenon that has no physiological explanation in current oncological understanding.
The Kind of Case Oncology Physicians Report
Composite archetype based on reported patterns — not a specific case
The terminal cancer patient given weeks to live whose tumors inexplicably vanish on follow-up scans. Oncologists call it spontaneous remission, but when it happens — in roughly 1 in 60,000 to 1 in 100,000 cases — the experience leaves an indelible mark on the treating physician, particularly when the remission coincides with a profound personal transformation in the patient's life that no immunological model can fully account for.
Read Real Cases in the Book →Physician Burnout by Specialty
Percentage reporting at least one symptom (Medscape, 2024)
Reader Ratings Distribution
Based on 1,018 Goodreads ratings
Why Oncology Physicians Encounter the Extraordinary
Oncology's long patient relationships and intimate engagement with dying create a specialty uniquely positioned to witness both ends of the extraordinary spectrum: inexplicable recoveries and transcendent deaths. The oncologist carries the cumulative weight of every patient lost and the vivid memory of every prognosis defied — and the gap between these experiences forms the space where the unexplained lives.
Physicians' Untold Stories speaks directly to oncologists who have watched tumors behave in ways their training said was impossible, or who have sat with dying patients during moments that felt like something more than a neurochemical event. Kolbaba's book honors the complexity of these experiences without reducing them to either miracle or coincidence.
Questions About Oncology and the Unexplained
How often does cancer truly spontaneously remit?
Is there a connection between psychological transformation and tumor regression?
What do oncologists experience when a terminal patient defies all prognosis?
Why do so many cancer patients experience visions near death?

Read the Stories That Changed Everything
Over 200 physicians interviewed. 26 stories that will challenge what you believe about life, death, and everything in between.
Buy on Amazon — 4.5★ (1,018 ratings)Browse by Specialty
Every medical specialty has its own encounters with the extraordinary. Explore stories from other fields.
